Other Studies
Other cohorts
A strength of the EDMUS software is that it lets its users use the software at their own convenience, completely independently from the EDMUS Coordinating Center.
Thus, several French and foreign teams have formed their own cohorts of patients and conducted research on them. The Multiple Sclerosis network in southern Italy, the Rennes and Nancy cohorts are a few examples of this activity.
Publications:
Trojano M, Avolio C, Manzari C et al. Multivariate analysis of predictive factors of multiple sclerosis with a validated method to assess clinical events. Journal of Neurology Neurosurgery and Psychiatry 1995; 58: 300-306.
Gayou A, Brochet B, Dousset V. Transitional progressive multiple sclerosis: a clinical and imaging study. Journal of Neurology, Neurosurgery and Psychiatry 1997; 63: 396-398.
Trojano M, Liguori M, Bosco Zimatore G et al. Age-related disability in multiple sclerosis. Annals of Neurology 2002; 51: 475-480.
Debouverie M, Louis S, Pittion-Vouyovitch S, Roederer T, Vespignani H. Multiple sclerosis with a progressive course from onset in Lorraine-Eastern France. Journal of Neurology 2007; 254: 1370-1375.
Trojano M, Pellegrini F, Fuiani A, Paolicelli D, Zipoli V, Zimatore GB, Di Monte E, Portaccio E, Lepore V, Livrea P, Amato MP New natural history of interferon-beta-treated relapsing multiple sclerosis. Annals of Neurology 2007; 61: 300-306.
Multicentre collaborative studies
led by other centers
EDMUS was also used in multicenter collaborative studies, led independently from the EDMUS Coordinating Center. Here are a few examples of such studies.
Publications:
Mikaeloff Y, Suissa S, Vallée L, Lubetzki C, Ponsot G, Confavreux C, Tardieu M, and the KIDMUS Study Group. First episode of acute CNS inflammatory demyelination in childhood: Prognostic factors for multiple sclerosis and disability. Journal of Pediatrics 2004; 144: 246-252.
Mikaeloff Y, Adamsbaum C, Husson B, Vallée L, Ponsot G, Confavreux C, Tardieu M, Suissa S, and the KIDMUS study group on Radiology. MRI prognostic factors for relapse after acute CNS inflammatory demyelination in childhood. Brain 2004; 124: 1942-1947.
Roxburgh RH, Seaman SR, Masterman T, Hensiek AE, Sawcer SJ, Vukusic S, Achiti I, Confavreux C, Coustans M, le Page E, Edan G, McDonnell GV, Hawkins S, Trojano M, Liguori M, Cocco E, Marrosu MG, Tesser F, Leone MA, Weber A, Zipp F, Miterski B, Epplen JT, Oturai A, Sorensen PS, Celius EG, Lara NT, Montalban X, Villoslada P, Silva AM, Marta M, Leite I, Dubois B, Rubio J, Butzkueven H, Kilpatrick T, Mycko MP, Selmaj KW, Rio ME, Sa M, Salemi G, Savettieri G, Hillert J, Compston DA. Multiple Sclerosis Severity Score: using disability and disease duration to rate disease severity. Neurology 2005; 64:1144-1151.