MS diagnostic criteria according to Poser et al.

Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann. Neurol. 1983; 13: 227-231

Categories Criteria
Space Time CSF
Clinically definite + + +
+ + -
Biologically definite + - +
- + +
Clinically probable + - -
- + -
Biologically probable - - +
Suspected - - -

Criteria for dissemination in Time

Generated directly from the second clinical event, if any.

msposer